IDEXX Cornerstone vs ezyVet: Veterinary Software Compared

A side-by-side look at IDEXX Cornerstone and ezyVet. See how these veterinary practice management systems compare on features, deployment, and PupPilot sync support.

26 Features Compared Both Sync with PupPilot Updated 2026

IDEXX Cornerstone On-Premise

Parent CompanyIDEXX Laboratories
Founded1985
DeploymentOn-Premise (server-based)
PricingLicense + Annual Support
User Base125,000+ professionals
Best ForMulti-doctor practices, specialty hospitals, and corporate groups that rely heavily on IDEXX diagnostics
PupPilot Sync Full Sync
VS

ezyVet Cloud

Parent CompanyIDEXX Laboratories
Founded2006
DeploymentCloud-Based
PricingSubscription (per provider)
User BaseLarge (IDEXX ecosystem)
Best ForMulti-location practices, emergency hospitals, and corporate groups that need enterprise cloud with IDEXX diagnostics
PupPilot Sync Full Sync

Feature-by-Feature Comparison

How IDEXX Cornerstone and ezyVet stack up across 26 core capabilities

FeatureIDEXX CornerstoneezyVet
EMR / Medical Records Core Clinical✓✓
SOAP Notes Core Clinical✓✓
AI SOAP / Transcription Core Clinical✗✗
Treatment Sheets / Whiteboard Core Clinical✓✓
Prescription Management Core Clinical✓✓
Digital Imaging / DICOM Core Clinical✓✓
Controlled Substance Logging Core Clinical✓✓
Appointment Scheduling Scheduling✓✓
Online Booking (Client Self-Service) Scheduling✓✓
Boarding / Hospitalization Scheduling✓✓
Inventory Management Financial✓✓
Invoicing & Billing Financial✓✓
Payment Processing Financial✓✓
Wellness Plans Financial✓✓
Client Communication (Reminders) Client Engagement✓✓
2-Way Messaging / Texting Client Engagement✓✓
Client Portal / App Client Engagement✓✓
Telemedicine / Video Client Engagement✗✗
Reporting & Analytics Operations✓✓
Multi-Location Support Operations✓✓
Mobile App / Access Operations✗✓
Digital Forms (Intake/Consent) Operations✗✓
IDEXX Lab Connection Lab Connections✓✓
Antech Lab Connection Lab Connections✓✓
Heska Lab Connection Lab Connections✓✓
IDEXX Web PACS Imaging Lab Connections✓✓

Strengths & Weaknesses

IDEXX Cornerstone

+ Seamless IDEXX diagnostics connection (VetConnect PLUS in-house + reference labs)
+ Customizable medical record templates for any specialty
+ Massive user base means extensive community knowledge and third-party support
− On-premise server dependency creates IT overhead and limits remote access
− Steeper learning curve — requires significant training investment
− No native AI features or modern cloud capabilities

ezyVet

+ Enterprise-grade cloud on AWS/GCP/Azure with robust workflow automation
+ Deep IDEXX diagnostics connection (VetConnect PLUS) and Web PACS imaging
+ rVetLink referral management streamlines specialty case coordination
− Complex system with steeper learning curve than simpler cloud PIMs
− Enterprise pricing may be too expensive for small solo practices
− No native AI transcription or SOAP generation features

PupPilot Syncs with Both

Whether your clinic runs IDEXX Cornerstone or ezyVet, PupPilot's AI phone answering service syncs directly with your practice management system to answer calls with real patient context. Learn more about how PupPilot works with IDEXX Cornerstone and ezyVet.

PupPilot + IDEXX Cornerstone Full Sync

Reads: Patient records, appointment schedule, medical history, medications, client info

Writes: Appointment booking, call notes, follow-up tasks

Connection: Direct database connection (on-premise server)

Setup: Days

PupPilot + ezyVet Full Sync

Reads: Patient records, appointment schedule, medical history, medications, client info

Writes: Appointment booking, call notes, follow-up tasks

Connection: Cloud API

Setup: Days

Frequently Asked Questions

IDEXX Cornerstone is Deepest IDEXX diagnostics connection; industry gold standard for specialty and referral practices. ezyVet is Enterprise cloud platform with deep IDEXX connection, workflow automation, and rVetLink referral management. The best choice depends on your clinic's size, specialty, and workflow preferences.

It depends on your priorities. IDEXX Cornerstone is best for Multi-doctor practices, specialty hospitals, and corporate groups that rely heavily on IDEXX diagnostics. ezyVet is best for Multi-location practices, emergency hospitals, and corporate groups that need enterprise cloud with IDEXX diagnostics. Consider factors like your budget, whether you prefer cloud or on-premise, and which lab systems you use.

Yes. PupPilot syncs with both IDEXX Cornerstone and ezyVet, providing AI-powered phone answering that reads patient records and appointment data directly from either system.

Yes, data migration between IDEXX Cornerstone and ezyVet is possible, though it typically requires careful planning and may involve a third-party migration service. Your PupPilot service would continue working seamlessly through the switch.